Reputational weight loss drugs Wegovy, Ozempic, and Mounjaro have been hailed as game-changers for those battling obesity and related disorders. These medications can improve quality of life by reducing the risk of dementia, controlling alcohol addiction, and enhancing heart and kidney health.
However, recent studies warn of potential long-term side effects associated with these drugs. Prolonged weight loss using GLP-1-based medications like semaglutide and tirzepatide can lead to significant muscle and bone loss. In fact, a study published in The Lancet Diabetes & Endocrinology found that muscle loss ranges from 25% to 39% of total weight lost over 36–72 weeks.
Muscle and bone mass loss can have far-reaching implications beyond increased risk of falls and fractures or reduced mobility in old age. Losing muscle mass can also disrupt blood sugar control, increasing the risk of Type 2 diabetes and its complications like blindness, nerve damage, and heart attacks.
To mitigate these effects while taking Ozempic and other GLP-1 medications, experts recommend a balanced diet rich in protein (1.2 to 1.6 grams per kilogram of body weight), incorporating meat, poultry, eggs, fish, dairy, nuts, seeds, legumes, beans, and soy products. Regular strength training and exercise, such as walking, hiking, or running, can also help maintain muscle strength and bone density.
Additionally, adequate calcium (1,000 mg) and vitamin D (800-1,000 IU) intake are crucial for maintaining strong bones. By taking these steps, individuals using Ozempic and other GLP-1 medications can minimize the risk of unexpected side effects and promote overall health.
Source: https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/not-just-fat-loss-weight-loss-drugs-are-causing-bone-and-muscle-loss-too-what-it-means/articleshow/116683832.cms