Researchers at the University of Copenhagen have made a breakthrough discovery that could lead to new treatments for age-related diseases and promote healthier aging. They found a protein called OSER1 that plays a key role in regulating longevity, offering insights into why some people live longer than others.
OSER1 is a newly identified protein linked to longer lifespans in humans and animals. The study suggests that OSER1 could be a target for future treatments aimed at extending life or preventing age-related diseases. This breakthrough opens up potential avenues for drug development and interventions that could promote healthier aging.
The researchers discovered OSER1 when they studied a larger group of proteins regulated by the major transcription factor FOXO, known as a longevity regulatory hub. They found 10 genes that, when manipulated, affected longevity. They decided to focus on one of these genes, called the OSER1 gene, which affected longevity most.
The study suggests that OSER1 could be a key player in regulating aging and longevity. The researchers hope to provide insights into the specific age-related diseases and aging processes that OSER1 influences. They also hope that the identification and characterization of OSER1 will provide new drug targets for age-related diseases such as metabolic diseases, cardiovascular and neurodegenerative diseases.
Overall, this discovery has significant implications for our understanding of human aging and could lead to the development of new treatments and interventions to promote healthier aging.
Source: https://neurosciencenews.com/oser1-longevity-gene-27617/