Researchers have made a breakthrough in developing a new treatment for Alzheimer’s disease, inspired by a compound found in common herbs like rosemary and sage. The stable derivative of carnosic acid, known as diAcCA, has shown promising results in mouse models of the disease.
DiAcCA has improved memory, neuron synapses, reduced inflammation, and increased removal of toxic proteins linked to Alzheimer’s. In mice with Alzheimer’s, the treatment boosted memory and improved cognitive function, reversing some symptoms of the disease.
The researchers found that diAcCA is more stable and better absorbed by the body than pure carnosic acid, allowing it to reach therapeutic levels in the brain within an hour. The treatment also didn’t have toxic effects on mice treated with it, reducing excessive buildups of proteins associated with Alzheimer’s damage.
While the results are promising, further clinical trials will be needed to confirm the effectiveness of diAcCA in human brains. However, the anti-inflammatory properties of carnosic acid and the potential for diAcCA to be used alongside existing treatments make this compound a promising area of research.
This breakthrough could also lead to new medications being developed more quickly, as diAcCA is a modified form of carnosic acid already known to be safe for consumption. The researchers are hopeful that diAcCA may improve the effects of existing amyloid antibody treatments and reduce their side effects.
Source: https://www.sciencealert.com/a-hidden-compound-in-rosemary-could-help-fight-alzheimers