A breakthrough discovery has been made in the quest to develop an effective treatment for snakebites, which claim over 200 lives a day and leave thousands more disabled. Researchers have created an antivenom that can protect against bites from 19 species of poisonous snakes, including coral snakes, mambas, cobras, and taipans.
The breakthrough comes thanks to the unique experience of Tim Friede, a self-taught snake expert who injected himself with venom from various species over nearly two decades. His blood contains antibodies that can neutralize multiple neurotoxins found in these snakes.
Scientists have isolated three key components – two antibodies and a small-molecule drug – which were tested on mice poisoned by venom from each of the 19 species. The combination offered 100% protection against six species, partial protection (20-40%) for another six, and complete protection across 13 species.
The development has sparked excitement among experts, who describe it as “revolutionary.” If approved for clinical use, this antivenom could significantly reduce the number of snakebite-related deaths and disabilities. Researchers are now investigating whether additional antibodies identified in Friede’s blood or other agents might offer protection against viperid snakes, which include rattlesnakes.
While further testing is needed to confirm its safety and efficacy in humans, the potential benefits of this breakthrough are undeniable. With over 400,000 people affected by snakebites each year, any development that can improve treatment options is a significant step forward.
Source: https://edition.cnn.com/2025/05/02/science/antivenom-snakebite-treatment-tim-friede