Testosterone supplements have become increasingly popular among young men in an effort to enhance physical performance. However, research suggests that these supplements may be linked to reduced sperm count.
According to Dr. Masaya Jimbo, a urologist and male infertility specialist, up to 25% of men who start testosterone replacement therapy (TRT) do not have their testosterone levels checked before beginning treatment. This lack of testing can lead to unintended consequences, including damage to fertility.
Testosterone is a hormone that plays a crucial role in maintaining men’s bone density, fat distribution, muscle strength and mass, facial and body hair, red blood cell production, sex drive, and sperm production. When testosterone levels decline with age, TRT may be prescribed to alleviate symptoms such as low libido and fatigue.
However, research has shown that TRT can have a “quick and dramatic” impact on fertility. The pituitary gland, which regulates hormone release, recognizes the presence of exogenous testosterone and reduces its production, leading to testicular shrinkage and halted sperm production. This effect can be permanent, taking up to three years for sperm to recover.
The risks associated with TRT are numerous, including worsening sleep apnea, acne, prostate cancer, breast enlargement, limited sperm production, and increased red blood cell production. Furthermore, many testosterone supplements have been found to contain active ingredients that may negatively impact T levels or make unsubstantiated claims about their effectiveness.
As fertility clinics see an increase in cases related to TRT, experts warn against the dangers of unchecked testosterone use. Biohacking, a trend that involves pursuing extreme measures for body optimization, has led to widespread adoption of TRT and other hormones. This trend may be perpetuating misinformation about the risks associated with testosterone supplements.
In light of these findings, it is essential for men considering TRT or taking testosterone supplements to consult with a healthcare professional and carefully weigh the potential benefits against the risks.
Source: https://eu.usatoday.com/story/life/health-wellness/2025/06/24/men-testosterone-supplements-infertility/84330772007