The suite of B vitamins, also known as the B complex, plays a crucial role in human health and disease. Researchers from Tufts University and elsewhere have found that these essential nutrients influence cognitive function, cardiovascular health, and even cancer.
Four of the B-vitamins cooperate as co-factors in critical activities in cells, making them vital for DNA synthesis, amino acid metabolism, and more. However, studying the B vitamins in isolation is challenging due to their complex role in human health.
One area of focus is cognitive health, particularly with vitamin B12. By age 75-80, 40% of people have a diminished ability to absorb food-bound B12, leading to nerve health decline and increased risk of dementia.
Studies have shown that elevated homocysteine levels, often caused by B12 deficiency, can slow cognitive decline. Researchers are now advocating for measuring B12 and homocysteine levels in patients with neurological issues or signs of dementia.
Additionally, vitamin B6 has been found to reduce inflammation, a key feature of chronic diseases like heart disease, diabetes, and arthritis. However, it’s essential to note that high doses of B6 can be toxic.
The role of folate (B9) in cognitive health is also being explored. Research suggests that high levels of folate might exacerbate B12 deficiency and contribute to cognitive issues.
The findings have significant implications for the diagnosis and treatment of dementia and cognitive decline. Researchers urge clinicians to consider measuring B vitamins and homocysteine levels as part of the evaluation process, potentially offering a more affordable and effective alternative to costly treatments.
Source: https://www.news-medical.net/news/20250804/New-research-unveils-vast-influence-of-B-vitamins-on-health-and-disease.aspx