Exceptionally Long-Lived People Suggest Key Differences in Biomarkers

Centenarians, who were once considered rare, have become commonplace. The world’s population of centenarians is growing rapidly, with numbers doubling every ten years since the 1970s. Scientists are now interested in understanding what determines a long and healthy life.

A recent study published in GeroScience has found some common biomarkers, including levels of cholesterol and glucose, that may be linked to exceptional longevity. Researchers compared the biomarker profiles of people who lived past 100 with those who did not, and investigated the link between the profiles and the chance of becoming a centenarian.

The study included data from 44,000 Swedes aged 64-99, who underwent health assessments and were followed through Swedish register data for up to 35 years. The researchers found that people who lived past 100 tended to have lower levels of glucose, creatinine, and uric acid, especially after the age of 60.

However, even among centenarians, there was no dramatic difference in these biomarkers. Instead, subtle variations were observed. For example, those with high glucose levels had a lower chance of reaching 100 years of age. The study suggests that factors such as nutrition and lifestyle may play a role in exceptional longevity.

While the study does not provide clear evidence on which genes or lifestyle factors are responsible for these biomarker values, it highlights the importance of monitoring kidney and liver function, glucose, and uric acid levels as we age.

Source: https://azertag.az/en/xeber/blood_of_exceptionally_long_lived_people_suggests_key_differences-3691055