Scientists at Oregon Health and Science University have made a groundbreaking discovery by creating early-stage human embryos using skin cell DNA. This technique, which could potentially overcome infertility issues due to old age or disease, involves manipulating the genetic code in skin cells and fertilizing it with sperm. The method uses almost any cell in the body as the starting point for life, offering hope to millions of people with infertility issues.
The technique, similar to one used to create Dolly the Sheep, starts by taking the nucleus from a skin cell and placing it inside a donor egg that has been stripped of its genetic instructions. The next stage involves persuading the egg to discard half of its chromosomes through a process called “mitomeiosis.” While the study showed promising results, with 82 functional eggs produced and some progressing to early embryo development, there is still much work to be done to perfect the technique.
Experts warn that the field needs further refinement, but the potential benefits are vast. This technology could help same-sex couples have genetically related children, older women who are no longer viable egg donors, men with low sperm count, and those whose cancer treatment has left them infertile. The study is a significant step towards in vitro gametogenesis, which aims to create sperm and eggs outside of the body.
As the research advances, it’s essential to build public trust and ensure robust governance to address safety concerns. Experts emphasize the need for continued open dialogue with the public about new advances in reproductive research. While this breakthrough is impressive, it’s crucial to consider the implications and responsibilities that come with such technology.
Source: https://www.bbc.com/news/articles/c4g2vyee0zlo