New research has found that repeated doses of acetaminophen in people aged 65 and over may significantly increase the risk of gastrointestinal, cardiovascular, and renal complications. A study published in Arthritis Care & Research analyzed data from over 180,000 individuals who had been prescribed paracetamol repeatedly, finding a higher incidence of peptic ulcers, heart failure, hypertension, and chronic kidney disease.
The researchers, led by Professor Weiya Zhang, emphasize the need for caution when prescribing acetaminophen for chronic pain conditions like osteoarthritis in older adults. Given its minimal pain-relief effect, the use of paracetamol as a first-line pain killer for long-term conditions needs careful consideration.
In contrast to previous guidelines that recommended paracetamol due to its perceived safety, the study highlights the potential risks associated with prolonged use in older adults. As such, healthcare providers must carefully weigh the benefits and risks when prescribing this medication to elderly patients.
Source: https://scitechdaily.com/new-study-exposes-hidden-risks-of-acetaminophen-in-older-adults