Aging is often viewed as a gradual process, but new research suggests that it occurs in two distinct peaks: one in the early 40s and another in the mid-60s. A study published in Nature Aging found that significant changes in molecules and microorganisms living in human bodies occur during these time periods.
According to senior study author Michael Snyder, PhD, at Stanford University, the mid-40s is a time of “dramatic change,” while the early 60s also experience significant shifts. These molecular changes affect various bodily functions, such as cardiovascular disease, skin and muscle health, immune regulation, and kidney function.
The researchers analyzed data from 108 participants between the ages of 25 and 75, tracking age-related changes in over 135,000 different molecules and microbes in their bodies. The analysis revealed that most molecules and microbes underwent major changes during two time periods: mid-40s and early 60s.
While the exact impact of these molecular shifts on aging is unknown, experts suggest that lifestyle changes can help manage or slow some of the associated changes. Staying active, eating well, managing stress, avoiding smoking, and reducing caffeine and alcohol consumption may be beneficial for overall health during these critical periods.
Experts emphasize that identifying and studying factors influencing these changes is crucial for future research, particularly for women in their mid-40s, where menopause or perimenopause may contribute to the observed changes.
Source: https://www.health.com/study-aging-peaks-8756326