A new study has uncovered a key reason behind the age-related shift in lung cancer risk, revealing that aging cells exhibit unusual behavior when it comes to iron metabolism. The research, published in Nature, found that older mice developed higher levels of NUPR1, a protein that causes cells to function as if they were deficient in iron, limiting their regeneration rates and putting restrictions on both healthy growth and cancerous tumors.
Source: https://www.sciencealert.com/the-risk-of-cancer-fades-as-we-get-older-and-we-may-finally-know-why