Alpha-Gal Syndrome Linked to Western Black-Legged Tick Bites

Alpha-gal syndrome (AGS), also known as red meat allergy, is a growing concern in the United States. Two recent studies have linked bites from western black-legged ticks to AGS, a potentially life-threatening condition that can cause severe gastrointestinal symptoms and anaphylaxis.

The US Centers for Disease Control and Prevention (CDC) estimates that AGS affects up to 450,000 Americans, but most cases are associated with lone star tick bites. The new studies reveal that black-legged tick bites may also be responsible for AGS in some individuals.

One case study from Maine detailed a woman who developed AGS symptoms after being bitten by a western black-legged tick in May 2022. She experienced gastrointestinal symptoms and anaphylaxis after eating red meat, and her condition improved significantly after switching to a vegetarian diet.

A similar case was reported in Washington state, where a woman who worked as a wildlife biologist developed AGS symptoms after being bitten by a western black-legged tick. Her symptoms resolved with treatment, but the incident highlights the need for public awareness about AGS outside the established lone star tick range.

Both studies emphasize the importance of tick bite prevention, healthcare provider education, and improved surveillance to combat AGS. The CDC is urging health professionals to be aware of the potential link between Ixodes ticks and AGS and to continue efforts focused on preventing tick bites and improving disease surveillance.

Source: https://www.cidrap.umn.edu/tick-borne-disease/research-ties-bites-2-more-types-ticks-red-meat-allergy