Bile Acids May Regulate Liver Cancer Growth and Immunotherapy Efficacy

Scientists at the Salk Institute have discovered that supplementing with bile acid UDCA can regulate tumor growth in mice with liver cancer. The researchers found that reducing a protein called BAAT, which produces conjugated bile acids, can also improve T cell function and enhance patient outcomes.

To weaken cancer, researchers recommend two steps:

1. Reduce the production of conjugated bile acids by eliminating the BAAT protein.
2. Supplement with UDCA, a bile acid that improves T cell function and promotes the recruitment of immune cells to the liver, ultimately controlling tumor growth and improving immunotherapy efficacy.

Source: https://scitechdaily.com/scientists-discover-readily-available-dietary-supplement-could-help-treat-liver-cancer