A recent study has discovered a new way to estimate the “biological age” of individual organs using blood samples from approximately 50,000 people. Researchers analyzed thousands of proteins in the blood and found that organ age is often older than the person’s actual age. This discrepancy can signal an increased risk of disease and earlier death.
On the other hand, a youthful brain and immune system are associated with a longer, healthier life. The study used machine learning algorithms to develop estimates of organ age based on plasma proteomics data. These estimates were found to be linked to healthspan and longevity.
The findings have been supported by previous research in this area, including a review article that discussed the development of measuring biological age using omics data. Another study analyzed the UK Biobank Pharma Proteomics Project to identify associations between plasma protein levels and genetics with health outcomes.
Overall, this new blood test has the potential to revolutionize the way we approach aging and age-related diseases.
Source: https://www.nature.com/articles/s41591-025-03814-4