Cannabis Use Linked to Working Memory Decline

Cannabis use has increased significantly worldwide, with the number of users growing from 180.6 million in 2011 to 219 million in 2021. The legalization of cannabis in many countries has contributed to this growth.

Research suggests that regular cannabis use can increase a person’s risk for certain health issues, including lung damage and potential links to dementia. A new study published in the journal analyzed data from over 1,000 young adults aged 22-36 who were categorized as heavy, moderate, or non-users of cannabis.

The study found that heavy cannabis users showed reduced brain activity during working memory tasks, with 63% of participants demonstrating lower activation levels. This effect was not significant when adjusting for confounding factors, but the researchers argue that it remains a concern.

Additional findings revealed that heavy cannabis users also had reduced brain activity in specific areas, including the dorsolateral prefrontal cortex and dorsomedial prefrontal cortex. These areas are crucial for cognitive functions such as working memory and executive function.

Experts quoted in the study emphasize the need for caution when it comes to cannabis use, particularly among young adults. Neurologist Clifford Segil notes that the study’s findings align with clinical observations of patients who report subjective memory difficulties after using cannabis regularly.

Clinical neuropsychologist Jasdeep S. Hundal agrees that the study highlights potential negative cognitive effects of cannabis, especially on working memory and executive function. He stresses the importance of informed discussions between doctors and patients, particularly those at high risk for Alzheimer’s disease or other memory-related conditions.

Source: https://www.medicalnewstoday.com/articles/can-cannabis-affect-memory-largest-study-yet-investigates