A review published in the World Allergy Organization Journal has raised concerns about the continued availability of diphenhydramine, a widely used over-the-counter medication. The study found that diphenhydramine impairs driving ability more than alcohol and poses significant public health risks due to its sedative effects and potential for abuse. Researchers recommend withdrawing diphenhydramine from both prescription and over-the-counter markets in favor of safer alternatives, such as second-generation antihistamines like cetirizine.
Source: https://conexiant.com/family-medicine/articles/diphenhydramine-risks-outweigh-benefits