In the final episode of “In Blood, Truth”, a pivotal moment in Dune: Prophecy’s first season, a telling line stands out: “Let us rid the Imperium of these witches forever.” The target of this declaration are the Bene Gesserit, a powerful female order that subtly influences events across the Dune universe. This comment is made by an unlikely speaker, whose character has shown no indication of such views until now.
However, in the world of Dune: Prophecy, nothing is as it seems. Characters have complex motivations, and those who appear harmless may be waiting for their moment to strike. As a result, this exchange between two characters appears as a straightforward villainous encounter but actually conceals deeper intentions that will unfold in future episodes.
Source: https://www.vulture.com/article/dune-prophecy-recap-season-1-episode-5-in-blood-truth.html