The US Food and Drug Administration (FDA) has recommended classifying 7-OH, a potent opioid-like compound found in unregulated tablets, gummies, and drink mixes sold at gas stations and convenience stores, as an illicit substance. This move would restrict access to these products, which are also sold online.
7-OH, formally known as 7-hydroxymitragynine, is often marketed as a way to help people relax, relieve pain, or improve their mood. However, studies suggest it’s more potent than morphine and can cause damage to the heart, liver, and potentially lead to seizures, digestive issues, shallow breathing, withdrawal symptoms, or even death.
The FDA has warned about the risks of 7-OH products being sold without warnings or control over quality or dosage, leading to a “recipe for public health disaster.” The agency’s recommendation will trigger a review by the Drug Enforcement Administration (DEA), which may classify 7-OH as a Schedule I substance, meaning it has no accepted medical use and a high potential for abuse.
The FDA is focusing on synthetic, concentrated versions of 7-OH, whereas products containing trace amounts of the chemical are considered safe. The DEA will review comments from the public before making a final decision.
Health and Human Services Secretary Robert F. Kennedy Jr. expressed concern about the widespread distribution of 7-OH products near schools and in low-income neighborhoods, describing them as “marketed for children.” Proponents of kratom argue that it’s useful for pain management, but experts warn about the risks associated with 7-OH.
The FDA has issued warning letters to seven companies selling 7-OH products, stating they cannot be lawfully added to conventional foods or dietary supplements. The agency will continue to test and monitor these products until they are deemed safe.
A Holistic Alternative Recovery Trust spokesperson said the FDA’s recommendation disregards how 7-OH is used in real-world scenarios. The American Kratom Association advocates for kratom regulation via labels, age restrictions, or limiting 7-OH concentration, but maintains kratom does not have a high potential for abuse.
Source: https://www.nbcnews.com/health/health-news/fda-asks-justice-department-classify-gas-station-products-opioid-effec-rcna221769