A comprehensive analysis by the Global Virus Network (GVN), representing eminent human and animal virologists from 80+ Centers of Excellence and Affiliates in 40+ countries, has highlighted the critical need for governments to address the threat of H5N1 avian influenza. The virus has affected nearly 1000 dairy cow herds and resulted in more than 70 human cases, including the first confirmed death in the U.S.
GVN experts stress the importance of enhanced surveillance, biosecurity measures, and preparedness for potential human-to-human transmission. They advocate for a multi-faceted approach to pandemic preparedness, which includes:
* Continuous monitoring of animals, including testing of milk and wastewater and individuals working with infected animals
* Accelerating genomic data sharing among global research networks
* Improved farm biosecurity using personal protective equipment and strict cleaning protocols
* Preparedness plans for the roll-out of self-administered diagnostic tests for farm workers and healthcare access for frontline medical staff
* Strengthening public health infrastructure, particularly in high-risk regions, with increased funding and support for response mechanisms
* Investment in predicting the phenotypes of avian influenza viruses from genetic data
* Rapid vaccine development and deployment, focusing on farm workers
* Prepositioned clinical studies to rapidly assess the properties of emerging virus strains and potential treatments
* International collaboration to track data, share research, and prepare for emerging viral threats
GVN virologists also emphasize the need for urgent efforts to understand and interrupt transmission in cattle through herd management and potential vaccination. They stress that strengthening surveillance at animal-human interfaces is crucial to guide effective prevention strategies.
The Global Virus Network calls on governments to take immediate action to address this growing threat, ensuring robust nationwide monitoring systems, maintaining trust with stakeholders, and implementing community-driven strategies for vaccine implementation.
Source: https://www.news-medical.net/news/20250429/Global-Virus-Network-urges-action-to-prevent-H5N1-pandemic.aspx