New research published in Nature Communications reveals a potential link between gut imbalances and autism symptoms in children. The study found that changes in the production of key neurotransmitters, such as serotonin, may play a crucial role in shaping behavioral symptoms associated with autism.
The researchers analyzed stool samples from 43 children with autism and compared them to 41 neurotypical children aged 8-17. They discovered that altered gut metabolites correlated with differences in brain structure and function in children with autism, particularly in regions related to interoception – the perception of internal bodily sensations.
This discovery suggests that targeting gut health may lead to new therapies for alleviating autism-related symptoms. The study highlights the importance of understanding the complex relationship between the gut microbiome and brain activity, which could have significant implications for the diagnosis and treatment of autism spectrum disorder.
According to Lisa Aziz-Zadeh, the first author of the study, “we demonstrated that gut metabolites impact the brain, and the brain, in turn, affects behavior.” The researchers hope that their findings will pave the way for innovative treatments that address the underlying causes of autism symptoms.
Source: https://neurosciencenews.com/gut-serotonin-asd-28636