Manganese Antioxidant Breakthrough Could Save Astronauts from Cosmic Radiation

Scientists have discovered the secret to how a type of bacteria called Deinococcus radiodurans can withstand extreme levels of radiation, and it’s a powerful antioxidant that could be used to protect humans too.

Deinococcus radiodurans, nicknamed “Conan the Bacterium,” is known for its ability to survive in harsh environments, including outside of the International Space Station for three years. The bacteria can also withstand acid, cold, and dehydration.

Researchers have found that a combination of manganese, phosphate, and a small peptide works together as an antioxidant, providing protection against radiation up to 28,000 times greater than what would be lethal to humans.

The breakthrough comes from understanding how this complex works to shield cells and proteins from radiation exposure. When the components bind together, they create a highly effective “secret sauce” that protects against radiation.

This discovery has significant implications for space exploration, as astronauts on deep-space missions are exposed to high levels of cosmic radiation. The researchers propose using the manganese antioxidant, called MDP, which is inspired by Deinococcus radiodurans, to mitigate these risks.

On Earth, the antioxidant could also be used to protect against accidents that release radiation. The team is now interested in exploring whether this triple complex exists in other organisms and if it’s responsible for their radiation-resistance.

Source: https://edition.cnn.com/2024/12/11/science/conan-the-bacterium-antioxidant/index.html