Research suggests that frequent marijuana use is associated with a significantly increased risk of oral cancer, with those who smoke both marijuana and cigarettes facing the highest odds of developing the disease.
A new study published in Preventive Medicine Reports found that people with daily or near-daily marijuana use were 325% more likely to develop some form of oral cancer over a five-year period compared to non-users. The risk was even higher for those who smoked both marijuana and cigarettes, with a 624% increase in oral cancer risk.
Study lead author Raphael Cuomo notes that cannabis smoke contains carcinogenic compounds similar to tobacco smoke, which can cause cellular damage leading to cancer. Researchers believe that the THC in marijuana may be suppressing the immune system, making users more vulnerable to cancer.
The study, which tracked over 45,000 patients, also found that more than 17 million Americans reported daily or near-daily marijuana use in 2022. The findings add to growing evidence suggesting that chronic cannabis use may contribute to cancer risk in tissues exposed to combustion products.
Overall, the increased risk of oral cancer associated with frequent marijuana use highlights the importance of being aware of the potential health risks and taking steps to reduce exposure to combustion products.
Source: https://www.usnews.com/news/health-news/articles/2025-08-01/heavy-weed-use-brings-high-risk-for-oral-cancers