Mark Duplass Opens Up About His ‘Exhausting’ Depression Regimen

Actor Mark Duplass has revealed the strict regimen he follows to manage his depression and anxiety. The 48-year-old star, known for his roles in “The Morning Show” and “Creep,” shared his system exclusively with Page Six at the Gotham Television Awards.

Duplass takes a consistent daily routine that includes getting enough sleep, exercise, and medication to keep his mental health in check. He has been on the same medication for nearly two decades and considers it a crucial part of his system. However, he also acknowledges that finding a balance can be exhausting and requires constant attention.

The indie filmmaker has been open about his struggles with anxiety and depression on social media for years. His recent post, which showed him smiling at an event but admitting to struggling with fear and sadness behind the scenes, resonated with fans and sparked a conversation about mental health.

Duplass realized that discussing his mental health issues wasn’t as demystified as he thought and decided to become more vocal about it. He believes that by sharing his experiences, he can help raise awareness and support for those struggling with similar issues.

Interestingly, Duplass finds it puzzling how depression affects people in different ways. One day, everything might seem fine, but the next, symptoms could be severe. Despite this complexity, he attributes his mental health struggles to his creativity and brain function, stating that he wouldn’t change them even if he could.

Source: https://pagesix.com/2025/06/08/celebrity-news/the-morning-show-star-reveals-his-strict-regimen-for-living-with-depression