The trend of “microdosing” weight loss medications like Ozempic is gaining popularity, with some people taking tiny amounts to avoid side effects and potentially lose weight. While some claim success, experts are divided on the effectiveness and safety of this approach.
Ozempic, a medication approved for type 2 diabetes, has also been used off-label for weight loss. However, its potent effects can lead to nausea, vomiting, and intense constipation. Some people, like Erica Liebman, a psychologist in Philadelphia, have turned to microdosing as a way to lose weight without experiencing these side effects.
Proponents of microdosing argue that smaller doses can still curb hunger and aid in weight loss. Dr. Daniel Drucker, a researcher at Mount Sinai Hospital, suggests that even tiny amounts may help reduce hunger. However, there is limited evidence to support the effectiveness of microdosing on its own, and experts warn that it may not be safe without medical guidance.
The placebo effect also plays a role in some cases, where people believe they’re experiencing benefits from the medication due to their expectations. Dr. Andrew Kraftson notes that “super responders” – individuals who quickly lose weight on these medications – might be responsible for any observed effects.
While microdosing may not be harmful, doctors are concerned about patients taking small doses without medical supervision. Stretching out doses can lead to expired medications, and some experts fear this trend will encourage the use of compounded weight loss drugs, which have health risks.
Some individuals, like Michael Hammer, who started microdosing Ozempic after experiencing severe side effects from standard doses, report successful weight loss. However, these results are not representative of the general population, and more research is needed to understand the efficacy and safety of microdosing.
As with any medication, it’s essential to consult a medical professional before attempting microdosing or adjusting dosages. The FDA has warned about compounded weight loss medications, which can be tailored for individual doses but may come with health risks. Ultimately, the effectiveness and safety of microdosing Ozempic remain unclear, and more research is needed to fully understand its benefits and drawbacks.
Source: https://www.nytimes.com/2024/12/05/well/ozempic-microdose-weight-loss.html