Migraines are no longer seen as an excruciating headache, but a complex neurological condition affecting millions worldwide. Recent research has led to a radical shift in understanding the disease and the development of new treatments.
A growing number of people are finding relief from migraines thanks to advancements in medication, such as gepants and monoclonal antibodies that block calcitonin gene-related peptide (CGRP). These treatments have already been life-changing for some sufferers. However, more work is needed to understand the underlying causes of migraines and to find effective solutions.
Migraine is not just a headache but a condition affecting multiple aspects of brain function, including sensitivity to light and sound, cognitive impairment, and nausea. Researchers are exploring alternative pathways and rethinking their approach to address this complexity.
Studies have identified genetic factors that predispose individuals to migraines and the potential role of the hypothalamus in triggering attacks. The search for environmental triggers is also underway, with researchers using artificial intelligence (AI) to track potential factors such as sleep disturbances, hormonal changes, or weather patterns.
While significant progress has been made, much work remains to be done. A better understanding of the brain and its role in migraines could unlock new treatments, offering hope to the one billion people worldwide affected by this condition.
Source: https://slguardian.org/migraine-a-radical-rethink-offers-hope-for-one-billion-sufferers