Research has found that oyster blood proteins can significantly enhance the effectiveness of antibiotics against antibiotic-resistant respiratory bacteria. A study published in the peer-reviewed journal PLOS One reveals that combining oyster blood proteins with standard antibiotics increased kill rates by two to 35 times, depending on the type of bacteria.
The research, conducted by Southern Cross University, involved testing Sydney rock oyster blood proteins in cell culture and found that these proteins disrupted the formation of biofilm, a protective coating created by groups of bacteria on surfaces inside human bodies. This allowed antibiotics to penetrate more effectively, increasing their kill rates.
Marine biologist Kirsten Benkendorff co-authored the report with lead researcher Kate Summer. “When we put the protein fraction from oyster blood in combination with antibiotics against different respiratory pathogens, it made the antibiotics work better,” she said.
The finding is significant as antibiotic resistance is a growing concern worldwide. Bacteria are becoming increasingly resistant to antibiotics, and by 2050, an estimated 10 million people could die annually from antimicrobial resistance. To combat this, researchers are exploring new treatments that can prolong the effectiveness of existing antibiotics.
Oysters, known for their antibacterial proteins, have been recognized as a valuable source of compounds that could help humans. Marine biologist Peter Speck noted that molluscs like oysters have evolved unique ways to deal with bacteria and are successful forms of life. The discovery has sparked interest in further research and development, which is expected to take around five to eight years.
The study’s findings offer a promising solution to the growing threat of antibiotic-resistant superbugs, and researchers are optimistic about the potential for oyster blood proteins to enhance antibiotic effectiveness against these pathogens.
Source: https://www.abc.net.au/news/2025-01-21/oyster-blood-helps-antibiotics-kill-respiratory-bacteria/104841500