Plasma Exchange Therapy Shows Early Signs in Anti-Aging Studies

A groundbreaking study published recently in the journal Aging Cell has shed light on the potential anti-aging benefits of plasma exchange therapy. The treatment, which involves exchanging a person’s blood plasma with donor plasma or substitute fluid, may help slow down biological aging.

Researchers conducted a small trial involving 42 participants aged 65, who received plasma exchange therapy over several months. The results showed lower concentrations of age-related compounds in their blood compared to a control group. While the study is promising, many scientists remain skeptical due to the lack of large-scale clinical trials and concerns about potential medical complications.

In hospitals, plasma exchange is commonly used to remove particles that accelerate disease progression, such as antibodies attacking the nervous system in multiple sclerosis. Proponents of anti-aging therapy claim it can also eliminate inflammatory antibodies and proteins driving biological aging. However, most research has been conducted on animals, and human trials have primarily focused on patients with age-related diseases.

Leading expert Dr. Caroline Alquist, interim co-director of the Hoxworth Blood Center at the University of Cincinnati, cautions that more research is needed to fully understand the benefits and risks of plasma exchange therapy for anti-aging purposes.

Source: https://www.uc.edu/news/articles/2025/05/could-plasma-exchange-therapy-help-you-live-longer.html