A researcher at the Centre for Pandemics and One-health Research (P1H) is studying the long-term effects of COVID-19 infections, particularly among adolescents.
The motivation behind this research stems from the researcher’s previous interest in post-infectious fatigue and chronic conditions after infections. They have been investigating this area for almost two decades, especially in pediatric patients. The COVID-19 pandemic brought attention to these long-term effects, which are common in other infectious diseases as well.
The aim of the current research is to understand the pathophysiology of long-term sequels of COVID-19, focusing on its biopsychosocial aspects. This includes exploring how mental processes influence bodily functions, such as the brain-immune axis.
This topic is crucial because it affects a significant portion of individuals with acute infections or specific acute infections. In adolescents, approximately 47% experience long-term sequels, including chronic fatigue syndrome, which can be debilitating. The majority will recover spontaneously, but this process can take time, and chronic conditions have a substantial impact on functional capabilities.
The researcher believes that studying pandemics and One-health is essential in understanding the late effects of COVID-19. Long COVID has highlighted the importance of considering both acute and chronic situations. By examining mental, psychological, and social phenomena, researchers can gain insights into this complex phenomenon.
A key aspect of the research involves identifying differences in the rate of long-term effects between younger children, adolescents, and adults. The study found that adolescents experienced a significant number of long-term sequels, while those in older age groups were more likely to experience severe acute COVID-19 with permanent organ damage. However, adolescents showed better prognosis if looked at over a five or ten year perspective.
The researcher’s goal is to contribute to the understanding of this phenomenon through high-quality research that can inform treatment, prophylaxis, and prevention strategies.
Source: https://www.med.uio.no/sustainit/english/centres/p1h/news-and-events/news/2024/0212_vegard_interview.html