Lung cancer among women who have never smoked is on the rise, according to a new study published in Lancet Respiratory Medicine. The disease is estimated to be the fifth leading cause of cancer-related mortality worldwide and is primarily found in women and Asian populations.
Researchers have identified genetic mutations as a key trigger for lung cancer in non-smokers. Fluctuations in female hormones during menopause can also increase the risk. Exposure to air pollution, including radon gas and PM 2.5 particles, can alter DNA and lead to cancer.
The study found that nearly 200,000 cases of adenocarcinoma were associated with exposure to air pollution. Lung cancer remains the leading cause of cancer-related morbidity worldwide, with approximately 2.5 million people diagnosed in 2022.
Experts say that changes in smoking patterns and exposure to air pollution are driving the increasing risk profile of lung cancer incidence by subtype. The rising burden of lung cancer is an area of concern, as most cases can be prevented.
The study’s lead author notes that there is accumulating evidence of a causal link between ambient PM pollution and an increased risk of adenocarcinoma. Efforts to reduce air pollution and tobacco use are crucial in preventing further rises in lung cancer cases among non-smokers.
Source: https://indianexpress.com/article/health-wellness/lung-cancer-among-women-non-smokers-on-rise-lancet-report-9816063