Scientists at Cognigenics have made a groundbreaking discovery in the field of neuroscience and mental health treatment. Their research, published in Genomic Psychiatry, shows that an RNA-based therapy called COG-201 can improve memory and reduce anxiety in animal models.
COG-201 targets the serotonin 5-HT2A receptor, which plays a crucial role in regulating mood, anxiety, and cognitive functions. By decreasing its expression, the researchers observed notable improvements in memory and reductions in anxiety-like behaviors in both mice and rats.
The therapy is delivered non-invasively through an intranasal method, making it a promising treatment for conditions like mild cognitive impairment and anxiety. The study provides both behavioral and neurophysiological evidence for the efficacy of COG-201.
While the results are promising, further studies, including trials in larger animals and eventually humans, will be necessary to fully understand the therapy’s potential and safety profile.
Source: https://neurosciencenews.com/rna-anxiety-memory-27620/