Scientists at Colossal Biosciences have created a genetically modified lab mouse with woolly mammoth-like traits, including curly whiskers and wavy hair that grows three times longer than an ordinary lab mouse. The goal of this experiment is to study the link between specific DNA sequences and physical traits that enabled the mammoth’s adaptation to life in cold climates.
Colossal Biosciences has identified genetic variants in which mammoths differed from their closest living relative, the Asian elephant. By pinpointing 10 variants related to hair length, thickness, texture, color, and body fat, scientists were able to create a woolly mouse with these traits. The company claims that this research is an important step toward resurrecting extinct animals.
The genetically modified rodent was created using three cutting-edge techniques to edit seven genes simultaneously. While the research outlined in an unpublished paper has been praised for its technical accuracy and efficiency, concerns have been raised about the mice’s ability to adapt to cold climates.
Colossal Biosciences plans to use this technology to recreate extinct animals such as mammoths, dodos, and Tasmanian tigers by editing the genome of each species’ closest living relative. The company aims to restore fauna to their natural habitat and mitigate the effects of climate change.
However, skeptics argue that the enormous sums of money invested in this project could be better spent elsewhere, particularly on conservation efforts that protect endangered animals.
Source: https://edition.cnn.com/2025/03/04/science/woolly-mouse-mammoth-resurrection-colossal/index.html