Scientists have made a major breakthrough in understanding the link between sleep patterns and Alzheimer’s disease. Research suggests that disrupted sleep, particularly issues with deep sleep and rapid eye movement (REM) sleep, is linked to increased risk and progression of Alzheimer’s and related dementias.
Studies show that poor sleep quality is associated with higher levels of amyloid beta (Aβ) and tau proteins, both hallmarks of Alzheimer’s disease. Older adults with fragmented or insufficient sleep often show elevated Aβ in brain regions critical for memory and cognition, such as the hippocampus and thalamus.
The link between sleep disturbances and Alzheimer’s has gained increasing attention as researchers uncover how sleep architecture changes in aging and how these changes may be early indicators of neurodegenerative disease. Slow-wave sleep (SWS), the deepest stage of non-rapid eye movement (NREM) sleep, is particularly important for brain detoxification.
Delayed REM sleep, which involves taking longer to reach the dream stage, has been linked to increased dementia risk over time. A recent study found that those who took longer to reach REM sleep were more likely to have Alzheimer’s and had higher levels of amyloid and tau proteins.
Experts recommend improving sleep habits to enhance the transition from light sleep to REM sleep, such as avoiding alcohol, treating sleep apnea, and limiting the use of certain sedatives and antidepressants that reduce REM sleep. By prioritizing sleep hygiene, individuals may be able to maintain cognitive health in aging and potentially slow the progression of Alzheimer’s.
Researchers are also investigating whether sleep-modifying medications could help slow Alzheimer’s progression. Future research should study the effects of these medications on disease progression, as they may provide new ways to prevent or delay the disease.
Source: https://www.thebrighterside.news/post/scientists-reveal-major-link-between-sleep-and-alzheimers-disease