A groundbreaking study has uncovered new information about Leonardo da Vinci’s genetic lineage, shedding light on his creative vision and artistic skills. Researchers Alessandro Vezzosi and Agnese Sabato spent over thirty years researching the artist’s family tree, identifying 400 individuals and tracing 15 direct descendants of Leonardo.
The study focused on Y chromosome analysis, which provided a link to Leonardo’s ancestors despite him never having direct children. DNA confirmation confirmed the existence of a continuous male-line lineage from Leonardo’s father Piero da Vinci. The team found six individuals who share identical Y chromosomes, confirming the genetic continuity of the Da Vinci family.
Key discoveries include the identification of a family tomb in Santa Croce Church in Vinci, Italy, where several relatives are believed to be buried. Anthropologists have been excavating the site, recovering bone fragments that could be linked to Leonardo’s family. Preliminary tests suggest that the remains are from a male, which could provide solid evidence to reconstruct Leonardo’s DNA.
The researchers are also exploring ancient manuscripts and drawings by Leonardo for traces of his DNA. Even something as simple as a fingerprint on a page could contain exploitable cells. Paleogenomic samples recovered from tombs in Vinci are being investigated to confirm the genetic lineage of the Da Vinci family.
New revelations about Leonardo’s life and family include the discovery of seven homes once owned by the Da Vinci family in Vinci, Italy. A charcoal drawing discovered on a fireplace mantle depicts a “Unicorn Dragon”, which shares stylistic features with Leonardo’s known works. The team has also made strides in uncovering the identity of Leonardo’s mother, suggesting she may have been an Oriental slave named Caterina.
The ongoing investigation is not only a scientific endeavor but also a cultural rediscovery. By reconnecting the present to the past, this project is reshaping our understanding of one of the greatest minds in history.
Source: https://dailygalaxy.com/2025/06/dna-analysis-uncover-leonardo-da-vincis-lineage-across-21-generations