A new study published in Science has found that scratching an itchy rash can actually provide some benefits, such as defense against bacterial skin infections. The researchers discovered that scratching releases a compound called substance P, which activates mast cells and helps fight off pathogens like Staphylococcus aureus. While this may seem counterintuitive, the study suggests that in certain contexts, the benefits of scratching may outweigh its negative effects on the skin. However, it’s essential to note that chronic itching can still cause significant damage to the skin. The researchers are now exploring new therapies that target mast cells to suppress inflammation and provide relief for dermatitis and other inflammatory skin conditions.
Source: https://medicalxpress.com/news/2025-01-shouldnt-itchy-rash.html